The indictment sent a shock wave through the GOP establishment, which is already reeling from a swath of criminal and ethics investigations. Three individuals, eight corporations and two political action committees connected to DeLay have been indicted as a result of the probe. In addition, the government's top procurement official, David Safavian, was arrested in September for obstructing a criminal investigation into über-lobbyist Jack Abramoff, a close DeLay ally. Abramoff himself is under criminal investigation for defrauding Indian tribes and was indicted for wire fraud in Florida in a separate case. Top White House aides, including Karl Rove and Scooter Libby, have been targeted by a special prosecutor investigating the outing of CIA agent Valerie Plame. Representative Duke Cunningham announced he would not run for re-election after overselling his house for $700,000 to a military industry lobbyist; he too has been indicted. FDA chief Lester Crawford resigned unexpectedly after just two months on the job, possibly because of failure to report his wife's sizable pharmaceutical-industry holdings. And DeLay's Senate counterpart, Bill Frist, is battling possible insider-trading charges for dumping millions in HCA stock, a company founded by his father and run by his brother, weeks before it plunged in value. The U.S. Attorney in Manhattan and the Securities and Exchange Commission opened an investigation into Frist and HCA in September.